Mei He, Ph.D.

School of Engineering - Chemical & Petroleum Engineering, Chemistry
Assistant Professor
Primary office:
785-864-4936
Multidisciplinary Research Building
Room 220E
University of Kansas
2030 Becker Drive
Lawrence, Kansas 66047
Second office:
Learned Hall
Room 4154



Summary

Dr. He is a tenure-track assistant professor at the University of Kansas after moving from the Kansas State University. She received her Ph.D. degree from the University of Alberta and postdoctoral training from the University of California, Berkeley. She also worked as the senior scientist at the University of Kansas Cancer Center between 2012-2014.

Education

Postdoctoral Scholar, Bioengineering, University of California-Berkeley

Doctor of Philosophy, Chemistry, University of Alberta, Canada

Master of Science, Pharmaceutical Chemistry, Chongqing University

Bachelor of Engineering, Chemical Engineering, Chongqing University

Teaching

Beside research, I am excited to interact with students, and would love to teach and mentor students in variable background across multiple levels (e.g., postdoc, graduate, undergraduate, and K-12). I have advised more than dozens of graduate and undergraduate students on their research projects in the field of Bioengineering, Chemical engineering, and Chemistry. I am strongly committed to motivating students to learn the skills of critical thinking and problem solving. I believe in a passionate, responsive and respectful manner to the unique atmosphere of a class can improve students' learning.

Teaching Interests

  • CHEM 401 Analytical Chemistry Lab
  • C&PE 732 Advanced Transport Phenomena

Research

Major efforts of our research group are dedicated to the innovative bioengineering solutions to human health, via device-level fabrication, material- level characterization, and biomolecular-level quantitation. We have developed a combination of 3D cell culture and bioprinting, 3D microfabrication of nano-biomaterials, biomedical microfluidic devices and sensing approaches, for designing, programming and monitoring biomimetic immunity, associated with extracellular vesicles-based communications. The long-standing interest is to understand immunity communication and delivery for translating into novel therapeutics and immunotherapy treatments against cancer and infectious diseases.

Research Interests

  • -- Bio-Inspired Nano/Micro Manufacturing
  • -- 3D Printing and Bioprinting of Living Tissue Foundry
  • -- Extracellular Vesicles for Cancer Immunotherapy
  • -- 3D Microfluidics and Nanotechnology

Service

Councilor, The American Electrophoresis Society (AES)

Vice Chair, ITSC-230 committee, ASABE Biosensor program

Founding Committee, MidWest Regional 3D printing Network

Member, International Society for Extracellular Vesicles (ISEV)

Member, The American Institute of Chemical Engineers (AIChE)

Member, The American Association of Cancer Research (AACR)

Member, The American Society of Mechanical Engineers (ASME)

Full Member, University of Kansas Cancer Center

Selected Publications

Zhang, P. Zhou, X. He, M. Shang, Y. Tetlow, L. Godwin, A. & Zeng, Y. (in press). Designable 3D Nanostructuring by Engineered Nanoparticle AssemblyAffords Ultrasensitive Microfluidic Sensing of Circulating Exosomes. Nature Biomedical Engineering.

Zhao, Z. McGill, J. & He, M. (2018). Microfluidic On-demand Engineering of Exosomes towards Cancer Immunotherapy. bioRxiv, 478875.

Zhu, Q. Hamilton, M. & He, M. (2018). 3D-PRINTING ENABLED MICRO-ASSEMBLING FOR MICROFLUIDIC ELECTROTRANSFECTION OF 3D-CULTURED CELLS AND TISSUES. In Proceedings of 23th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019) 3.

ZHU, Q. & HE, M. (2018). 3D ADDITIVE MANUFACTURING AND MICRO-ASSEMBLY FOR TRANSFECTION OF 3D-CULTURED CELLS AND TISSUES. In ASME 2018 13th International Manufacturing Science and Engineering Conference

ZHU, Q. HEON, M. ZHAO, Z. & HE, M. (2018). Microfluidic Engineering of Exosomes: Editing Cellular Messages for Precision Therapeutics. LAB ON CHIP, 18, 1690-1703.

Hochendoner, P. Zhao, Z. & HE, M. (2018). Diagnostic Potential of Tumor Exosomes. In . (Ed.), Diagnostic and Therapeutic Applications of Exosomes in Cancer, Elsevier Press.

Sibbitts, J. & He, M. (2017). 3D Printing of Microfluidics for Point of Care Diagnosis. In Proceedings of the ASME 2017 International Manufacturing Science & Engineering Conference (pp. 56-60).

Zhao, Z. Sibbitt, J. & HE, M. (2017). ON-CHIP HARVESTING AND PHOTO-RELEASE OF IMMUNOGENIC EXTRACELLULAR VESICLES FOR CANCER IMMUNOTHERAPY.

He, M. Godwin, A. & Zeng, Y. (2016). Microfluidic Multistage Integration for Analysis of Circulating Exosomes. In . (Ed.), Microfluidic Methods for Molecular Biology. Springer Publishing.

Plevniak, K. Campbell, M. & He, M. (2016). 3D Printed Microfluidic Mixer for Point-of-Care Diagnosis of Anemia. In The 38th IEEE EMBC Proceedings (pp. 267-270).

Plevniak, K. Campbell, M. Myers, T. Hodges, A. & He, M. (2016). 3D Printed Auto-mixing Chip Enables Rapid Smartphone Diagnosis of Anemia. Biomicrofluidics, 10, 054113.

Zhao, Z. Yang, Y. Zeng, Y. & He, M. (2016). A Microfluidic ExoSearch Chip for Multiplexed Exosome Detection Towards Blood-based Ovarian Cancer Diagnosis. Lab on a Chip, 16, 489-496.

He, M. & Zeng, Y. (2016). Microfluidic Exosome Analysis towards Liquid Biopsy for Cancer. Journal of Laboratory Automation, 21, 599-608.

Zhang, P. He, M. & Zeng, Y. (2016). Ultrasensitive microfluidic analysis of circulating exosomes using a nanostructured graphene oxide/polydopamine coating. Lab on a Chip, 16, 3033-3042.

Plevniak, K. & He, M. (2015). Microfluidic Technology: the Next–generation Drug Discovery Tool. Drug Target Review, 2(3), 18-20.

He, M. Godwin, A. & Zeng, Y. (2014). Integrated Microfluidic Phenotyping of Tumor-Derived Exosomes. In The proceedings of 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS) (pp. 111-113).

He, M. Zhao, Z. Godwin, A. K., & Zeng, Y. (2014). Rapid On-chip Molecular Profiling of Circulating Exosomes for Early Detection of Ovarian Cancer. In The proceedings of 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS) (pp. 1071-1073).

He, M. Crow, J. Roth, M. Zeng, Y. & Godwin, A. K. (2014). Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology. Lab on a Chip, 14, 3773-3780.

Zhao, Z. & He, M. (2014). Microfluidic Technologies: Lifting the Veil of Exosomes. MOJ Proteomics Bioinformatics, 1(3), 00014.

Kim, D. Karns, K. Tia, S. Q., He, M. & Herr, A. E. (2012). Electrostatic protein immobilization using charged polyacrylamide gels and cationic detergent microfluidic Western blotting. Analytical Chemistry, 84, 2533-2540.

He, M. Zeng, Y. Jemere, A. & Harrison, D. J. (2012). Tunable thick polymer coatings for on-chip electrophoretic protein and peptide separation. Journal of Chromatography A, 1241, 112-116.

He, M. (2011). High-throughput Microfluidic Proteomics, Lambert Academic Publishing.

He, M. Novak, J. Julian, B. A., & Herr, A. E. (2011). Membrane-assisted online renaturation for automated microfluidic lectin blotting. Journal of the American Chemical Society, 133, 19610-19613.

Tia, S. Q., He, M. Kim, D. & Herr, A. E. (2011). Multi-analyte on-chip native western blotting. Analytical Chemistry, 83, 3581–3588.

He, M. & Herr, A. E. (2010). Automated microfluidic protein immunoblotting. Nature Protocols, 5, 1844-1856.

He, M. Bao, J. Zeng, Y. & Harrison, D. J. (2010). Parameters governing reproducibility of flow properties of porous monoliths photopatterned within microfluidic channels. Electrophoresis, 31, 2422-2428.

He, M. & Herr, A. E. (2010). Polyacrylamide gel photopatterning enables automated protein immunoblotting in a two-dimensional microdevice. Journal of the American Chemical Society, 132, 2512-2513.

He, M. & Herr, A. E. (2009). Microfluidic polyacrylamide gel electrophoresis with in-situ immunoblotting for native protein analysis. Analytical Chemistry, 81, 8177-8184.

He, M. Zeng, Y. Sun, X. & Harrison, D. J. (2008). Confinement effects on the morphology of photopatterned porous polymer monoliths for capillary and microchip electrophoresis of proteins. Electrophoresis, 29, 2980-2986.

Zeng, Y. He, M. & Harrison, D. J. (2008). Microfluidic Self-Patterning of Large-Scale Crystalline Nanoarrays for High-Throughput Continuous DNA Fractionation. Angewandte Chemie International Edition, 47, 6388-6391.

Selected Presentations

Selected Grants

Selected Awards & Honors


Upcoming Events and Deadlines

Sunday, April 14th - GEA5K | Starts at 8am | 2101 Constant Ave 

Friday, May 3rd - Paul Willhite's Retirement Celebration | 6-8pm | Beren Petroleum Conference Center

Saturday, May 4th - Annual Departmental Awards Banquet | 5:30 - 8:30pm | KU Memorial Union's Ballroom

Saturday, May 18th - School of Engineering Recognition Ceremony | starts at 8am | Allen Fieldhouse


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