Mei He, Ph.D.
School of Engineering - Chemical & Petroleum Engineering, ChemistryRoom 220E
Room 4154
Dr. He is a tenure-track assistant professor at the University of Kansas after moving from the Kansas State University. She received her Ph.D. degree from the University of Alberta and postdoctoral training from the University of California, Berkeley. She also worked as the senior scientist at the University of Kansas Cancer Center between 2012-2014.
Education
Postdoctoral Scholar, Bioengineering, University of California-Berkeley
Doctor of Philosophy, Chemistry, University of Alberta, Canada
Master of Science, Pharmaceutical Chemistry, Chongqing University
Bachelor of Engineering, Chemical Engineering, Chongqing University
Teaching
Beside research, I am excited to interact with students, and would love to teach and mentor students in variable background across multiple levels (e.g., postdoc, graduate, undergraduate, and K-12). I have advised more than dozens of graduate and undergraduate students on their research projects in the field of Bioengineering, Chemical engineering, and Chemistry. I am strongly committed to motivating students to learn the skills of critical thinking and problem solving. I believe in a passionate, responsive and respectful manner to the unique atmosphere of a class can improve students' learning.
Teaching Interests
- CHEM 401 Analytical Chemistry Lab
- C&PE 732 Advanced Transport Phenomena
Research
Major efforts of our research group are dedicated to the innovative bioengineering solutions to human health, via device-level fabrication, material- level characterization, and biomolecular-level quantitation. We have developed a combination of 3D cell culture and bioprinting, 3D microfabrication of nano-biomaterials, biomedical microfluidic devices and sensing approaches, for designing, programming and monitoring biomimetic immunity, associated with extracellular vesicles-based communications. The long-standing interest is to understand immunity communication and delivery for translating into novel therapeutics and immunotherapy treatments against cancer and infectious diseases.
Research Interests
- -- Bio-Inspired Nano/Micro Manufacturing
- -- 3D Printing and Bioprinting of Living Tissue Foundry
- -- Extracellular Vesicles for Cancer Immunotherapy
- -- 3D Microfluidics and Nanotechnology
Service
Councilor, The American Electrophoresis Society (AES)
Vice Chair, ITSC-230 committee, ASABE Biosensor program
Founding Committee, MidWest Regional 3D printing Network
Member, International Society for Extracellular Vesicles (ISEV)
Member, The American Institute of Chemical Engineers (AIChE)
Member, The American Association of Cancer Research (AACR)
Member, The American Society of Mechanical Engineers (ASME)
Full Member, University of Kansas Cancer Center
Selected Publications
ZHU, Q. HEON, M. ZHAO, Z. & HE, M. (2018). Microfluidic Engineering of Exosomes: Editing Cellular Messages for Precision Therapeutics. LAB ON CHIP, 18, 1690-1703.
Plevniak, K. Campbell, M. Myers, T. Hodges, A. & He, M. (2016). 3D Printed Auto-mixing Chip Enables Rapid Smartphone Diagnosis of Anemia. Biomicrofluidics, 10, 054113.
Zhao, Z. Yang, Y. Zeng, Y. & He, M. (2016). A Microfluidic ExoSearch Chip for Multiplexed Exosome Detection Towards Blood-based Ovarian Cancer Diagnosis. Lab on a Chip, 16, 489-496.
He, M. & Zeng, Y. (2016). Microfluidic Exosome Analysis towards Liquid Biopsy for Cancer. Journal of Laboratory Automation, 21, 599-608.
Zhang, P. He, M. & Zeng, Y. (2016). Ultrasensitive microfluidic analysis of circulating exosomes using a nanostructured graphene oxide/polydopamine coating. Lab on a Chip, 16, 3033-3042.
Plevniak, K. & He, M. (2015). Microfluidic Technology: the Next–generation Drug Discovery Tool. Drug Target Review, 2(3), 18-20.
He, M. Crow, J. Roth, M. Zeng, Y. & Godwin, A. K. (2014). Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology. Lab on a Chip, 14, 3773-3780.
Kim, D. Karns, K. Tia, S. Q., He, M. & Herr, A. E. (2012). Electrostatic protein immobilization using charged polyacrylamide gels and cationic detergent microfluidic Western blotting. Analytical Chemistry, 84, 2533-2540.
He, M. Zeng, Y. Jemere, A. & Harrison, D. J. (2012). Tunable thick polymer coatings for on-chip electrophoretic protein and peptide separation. Journal of Chromatography A, 1241, 112-116.
He, M. Novak, J. Julian, B. A., & Herr, A. E. (2011). Membrane-assisted online renaturation for automated microfluidic lectin blotting. Journal of the American Chemical Society, 133, 19610-19613.
Tia, S. Q., He, M. Kim, D. & Herr, A. E. (2011). Multi-analyte on-chip native western blotting. Analytical Chemistry, 83, 3581–3588.
He, M. & Herr, A. E. (2010). Automated microfluidic protein immunoblotting. Nature Protocols, 5, 1844-1856.
He, M. Bao, J. Zeng, Y. & Harrison, D. J. (2010). Parameters governing reproducibility of flow properties of porous monoliths photopatterned within microfluidic channels. Electrophoresis, 31, 2422-2428.
He, M. & Herr, A. E. (2010). Polyacrylamide gel photopatterning enables automated protein immunoblotting in a two-dimensional microdevice. Journal of the American Chemical Society, 132, 2512-2513.
He, M. & Herr, A. E. (2009). Microfluidic polyacrylamide gel electrophoresis with in-situ immunoblotting for native protein analysis. Analytical Chemistry, 81, 8177-8184.
He, M. Zeng, Y. Sun, X. & Harrison, D. J. (2008). Confinement effects on the morphology of photopatterned porous polymer monoliths for capillary and microchip electrophoresis of proteins. Electrophoresis, 29, 2980-2986.
Zeng, Y. He, M. & Harrison, D. J. (2008). Microfluidic Self-Patterning of Large-Scale Crystalline Nanoarrays for High-Throughput Continuous DNA Fractionation. Angewandte Chemie International Edition, 47, 6388-6391.
