Mei He, Ph.D.
School of Engineering - Chemical & Petroleum Engineering, ChemistryRoom 220E
Room 4154
Dr. He is a tenure-track assistant professor at the University of Kansas. She received her PhD degree from the University of Alberta and postdoctoral training from the University of California, Berkeley. She is the Councilor of the American Electrophoresis Society, founding committee for the MidWest 3D technology society, and the founder of Clara Biotech Inc. Dr. He Received NIH Maximizing Investigator’s Research Award for Early Stage Investigators in 2019. She also received the Lab on Chip Outstanding Reviewer for the year of 2018 and Emerging Investigator in 2019. She also received 2018 SLAS Technology Readers Choice Award.
Education
Postdoctoral Scholar, Bioengineering, University of California-Berkeley
Doctor of Philosophy, Chemistry, University of Alberta, Canada
Master of Science, Pharmaceutical Chemistry, Chongqing University
Bachelor of Engineering, Chemical Engineering, Chongqing University
Teaching
Besides research, I am excited to interact with students, and would love to teach and mentor students in variable background across multiple levels (e.g., postdoc, graduate, undergraduate, and K-12). I have advised more than dozens of graduate and undergraduate students on their research projects in the field of Bioengineering, Chemical engineering, and Chemistry. I am strongly committed to motivating students to learn the skills of critical thinking and problem solving. I believe in a passionate, responsive and respectful manner to the unique atmosphere of a class can improve students' learning.
Teaching Interests
- CHEM 401 Analytical Chemistry Lab
- C&PE 732 Advanced Transport Phenomena
Research
Our research group seeks obtaining precise definition and control of immunity at the molecular level to tissue level, via extracellular vesicles and exosomes -mediated delivery and biological programming strategies, which can be employed in advancing cancer immunotherapy, regenerative medicine, and precision therapeutics. The long-standing interest is to understand immunity communication and delivery for translating into novel therapeutics and treatments against cancers, autoimmune diseases, and infectious diseases which immune responses are the central player.
Research Interests
- -- 3D Printing and Bioprinting of Living Tissue Foundry
- -- Extracellular Vesicles for Cancer Immunotherapy and Drug Delivery
- -- 3D Microfluidics and Nanotechnology
Service
Councilor, The American Electrophoresis Society (AES)
Founding Committee, MidWest Regional 3D printing Network
Member, International Society for Extracellular Vesicles (ISEV)
Member, The American Institute of Chemical Engineers (AIChE)
Member, The American Association of Cancer Research (AACR)
Member, Biomedical Engineering Society (BMES-CMBE)
Full Member, University of Kansas Cancer Center
Selected Publications
Thippabhotla, S. Zhong, C. & He, M. (2019). 3D cell culture stimulates the secretion of in vivo like extracellular vesicles. Nature Scientific Reports, 9, 13012.
Zhang, P. Zhou, X. He, M. Shang, Y. Tetlow, A. L., Godwin, A. K., & Zeng, Y. (2019). Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip. NATURE BIOMEDICAL ENGINEERING, 3(6), 438-451. DOI:10.1038/s41551-019-0356-9
ZHU, Q. HEON, M. ZHAO, Z. & HE, M. (2018). Microfluidic Engineering of Exosomes: Editing Cellular Messages for Precision Therapeutics. LAB ON CHIP, 18, 1690-1703.
Zhu, Q. Hamilton, M. & He, M. (2018). 3D-PRINTING ENABLED MICRO-ASSEMBLING FOR MICROFLUIDIC ELECTROTRANSFECTION OF 3D-CULTURED CELLS AND TISSUES. In Proceedings of 23th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019) 3.
Zhao, Z. McGill, J. & He, M. (2018). Microfluidic On-demand Engineering of Exosomes towards Cancer Immunotherapy. bioRxiv, 478875.
Plevniak, K. Campbell, M. Myers, T. Hodges, A. & He, M. (2016). 3D Printed Auto-mixing Chip Enables Rapid Smartphone Diagnosis of Anemia. Biomicrofluidics, 10, 054113.
Zhao, Z. Yang, Y. Zeng, Y. & He, M. (2016). A Microfluidic ExoSearch Chip for Multiplexed Exosome Detection Towards Blood-based Ovarian Cancer Diagnosis. Lab on a Chip, 16, 489-496.
He, M. & Zeng, Y. (2016). Microfluidic Exosome Analysis towards Liquid Biopsy for Cancer. Journal of Laboratory Automation, 21, 599-608.
Zhang, P. He, M. & Zeng, Y. (2016). Ultrasensitive microfluidic analysis of circulating exosomes using a nanostructured graphene oxide/polydopamine coating. Lab on a Chip, 16, 3033-3042.
He, M. Novak, J. Julian, B. A., & Herr, A. E. (2011). Membrane-assisted online renaturation for automated microfluidic lectin blotting. Journal of the American Chemical Society, 133, 19610-19613.
He, M. & Herr, A. E. (2010). Automated microfluidic protein immunoblotting. Nature Protocols, 5, 1844-1856.
He, M. & Herr, A. E. (2010). Polyacrylamide gel photopatterning enables automated protein immunoblotting in a two-dimensional microdevice. Journal of the American Chemical Society, 132, 2512-2513.
